Dapiprazole Hydrochloride

CAS No. 72822-13-0

Dapiprazole Hydrochloride( —— )

Catalog No. M19044 CAS No. 72822-13-0

Dapiprazole Hydrochloride is an alpha-1-adrenergic antagonist that acts by blocking alpha-adrenergic receptors in the smooth muscle of blood vessels (arteries, arterioles and veins), gastrointestinal tract, and radial smooth muscle of the iris.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
10MG 39 In Stock
25MG 80 In Stock
50MG 123 In Stock
100MG 177 In Stock
200MG 267 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Dapiprazole Hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Dapiprazole Hydrochloride is an alpha-1-adrenergic antagonist that acts by blocking alpha-adrenergic receptors in the smooth muscle of blood vessels (arteries, arterioles and veins), gastrointestinal tract, and radial smooth muscle of the iris.
  • Description
    Dapiprazole Hydrochloride is an alpha-1-adrenergic antagonist that acts by blocking alpha-adrenergic receptors in the smooth muscle of blood vessels (arteries, arterioles and veins), gastrointestinal tract, and radial smooth muscle of the iris.(In Vivo):Dapiprazole hydrochloride (0-10 mg/kg or 0-3 mg/mice; i.p. or i.c.v.; once) reduces the overall severity of the opiate withdrawal symptoms in mice.
  • In Vitro
    ——
  • In Vivo
    Dapiprazole hydrochloride (0-10 mg/kg or 0-3 mg/mice; i.p. or i.c.v.; once) reduces the overall severity of the opiate withdrawal symptoms in mice. Animal Model:Swiss Albino male CD-1 mice weighing 20 -25 g, acute dependence model Dosage:5, 7.5 and 10 mg/kg (i.p.) or 0.5, 1 and 3 mg/mice (i.c.v.), once Administration:Intraperitoneal injection or intracerebroventricular administration, once Result:Decreased jumping behavior, head shakes and paw shakes when administered just before naloxone.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    α1-adrenergic receptor
  • Research Area
    Others-Field
  • Indication
    ——

Chemical Information

  • CAS Number
    72822-13-0
  • Formula Weight
    361.92
  • Molecular Formula
    C19H28ClN5
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : ≥ 31 mg/mL; 85.66 mM
  • SMILES
    Cc1ccccc1N1CCN(CC1)CCc1nnc2n1CCCC2.Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hogan TS., et al. Dose-response study of dapiprazole HCl in the reversal of mydriasis induced by 2.5% phenylephrine. J Ocul Pharmacol Ther. 1997 Aug;13(4):297-302.
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